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World-first tooth-regrowing drug will be given to humans in September


The world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030.

The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side effects. Following this 11-month first stage, the researchers will then trial the drug on patients aged 2-7 who are missing at least four teeth due to congenital tooth deficiency, which is estimated to affect 1% of people. Molecular biologist and dentist Takahashi has been working on tooth regeneration since 2005, and hopes this treatment won't just be for congenital dental conditions but for anyone who has lost teeth, at any age.

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