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World's first "Synthetic Biological Intelligence" runs on living human cells | The CL1, offers a whole new kind of computing intelligence


The world's first "biological computer" that fuses human brain cells with silicon hardware to form fluid neural networks has been commercially launched, ushering in a new age of AI technology. The CL1, from Australian company Cortical Labs, offers a whole new kind of computing intelligence – one…

"We’ve enjoyed a series of critical breakthroughs in recent years, most notably our research in the journal Neuron, through which cultures were embedded in a simulated game-world, and were provided with electrophysiological stimulation and recording to mimic the arcade game Pong. New Atlas readers may already be familiar with Cortical Labs and its formative steps towards SBI, with Loz Blain covering the early advances of this self-adjusting neural network capable of adjusting and adapting to forge new, stimuli-responsive pathways in processing information. In 2022, the team demonstrated how rodent- and human-induced pluripotent stem cells (hiPSCs) integrated into high-density multielectrode arrays (HD-MEAs) based on complementary metal–oxide–semiconductor (CMOS) technology could be electro-physiologically stimulated to forge autonomous, highly efficient information-exchange paths.

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