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World’s first pig lung transplant in brain-dead man lasts nine days in China | The pig was genetically modified using the CRISPR genome editor.
Genetically modified lung functioned for nine days in latest development in xenotransplantation aimed at solving organ shortage crisis
Surgeons have transplanted a lung from a genetically modified pig into a brain dead human recipient for the first time and found it functioned for nine days, researchers have revealed. Writing in the journal Nature Medicine, researchers in China reported how they transplanted the left lung from a Chinese Bama Xiang donor pig with six genetic modifications into a 39-year-old brain dead male recipient. “Continued efforts are needed to optimise immunosuppressive regimens, refine genetic modifications, enhance lung preservation strategies and assess long-term graft function beyond the acute phase,” they wrote.
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