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World's first stem cell treatment restores vision in cornea-damaged patients
Three individuals with vision disabilities experienced eyesight improvements after receiving stem-cell transplants targeting damaged corneas.
When this vital source of rejuvenation is depleted—a disorder known as limbal stem-cell deficit (LSCD)—scar tissue forms on the cornea, eventually leading to blindness. As part of the surgery, the team scraped off the layer of scar tissue covering the damaged cornea in only one eye, then stitched on epithelial sheets derived from a donor and placed a soft protective contact lens on top. The grafts did not form tumors—a known risk of growing iPS cells—and did not show clear signs of being attacked by the recipients’ immune systems, even in two patients who did not receive immunosuppressant drugs.
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