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Zero calorie sweetener linked to blood clots and heart disease, study finds


In a head-to-head comparison, drinks containing erythritol, a sweetener in stevia and keto products, raised the risk of blood clots while sugar water did not.

“What is remarkable is that in every single subject, every measure of platelet responsiveness (clotting) went up following the erythritol ingestion,” said lead study author Dr. Stanley Hazen, director of the Center for Cardiovascular Diagnostics and Prevention at the Cleveland ClinicLerner Research Institute. Consuming a drink with an equal amount of glucose, or sugar, did not affect blood platelet activity in another group of 10 people, said Hazen, who is also the Jan Bleeksma chair in vascular cell biology and atherosclerosis at the Cleveland Clinic. However, the amount of erythritol used in each drink in the study — 30 grams — was the equivalent of what is included in typical sugar-free sodas, ice creams or muffins, of which people often eat more than one, Hazen said.

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